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PT-141 dosage calculator.
Reconstituting PT-141? Enter the mg in the vial, the bacteriostatic water you add, and your target dose. You get the exact concentration, the volume to draw in mL, and the units on a U-100 syringe. No rounding, no account, and the full math is shown every time.
Units shown for a U-100 insulin syringe (1 mL = 100 units). No rounding · the full math is above.
How the math works
Three steps, no hand-waving.
Reconstitution is simple arithmetic. The only thing that matters is that it is exact, and that you can see every step.
Vial mg ÷ BAC water mL = mg/mL. A 10 mg vial in 2 mL of water is 5.0000 mg/mL.
Target dose ÷ concentration = mL to draw. 1.75 mg ÷ 5.0000 mg/mL = 0.3500 mL.
Draw mL × 100 = units on a U-100 insulin syringe. 0.3500 mL = 35 units.
Background
What PT-141 reconstitution is
PT-141 (bremelanotide) is a synthetic cyclic peptide and melanocortin-receptor agonist. The FDA approved it in 2019 under the brand Vyleesi for hypoactive sexual desire disorder in premenopausal women, where it is dosed at 1.75 mg subcutaneously. It is an analog of melanotan II and acts centrally rather than on blood flow. Research vials are supplied as a lyophilized powder reconstituted with bacteriostatic water; concentration is the mg in the vial divided by the mL of water you add. This calculator runs that arithmetic exactly.
- Reconstitution built into the dose logger, not a separate tool
- 28-day BAC water expiry countdown per vial
- Doses remaining and refill warnings, all derived
- Local-first · no account, data stays on your device
FAQ
PT-141 reconstitution questions, answered.
How do you calculate a PT-141 dose?
Divide the mg of PT-141 in the vial by the mL of bacteriostatic water you add for the concentration in mg/mL. Then divide your target dose (in mg) by that concentration for the draw volume in mL, and multiply by 100 for units on a U-100 insulin syringe.
How much BAC water for a 10mg PT-141 vial?
There is no single correct amount. 2 mL gives 5 mg/mL; more water lowers the concentration and gives a larger draw. Enter the amount you plan to add and the calculator returns your exact numbers.
How many units is 1.75 mg of PT-141?
It depends on the concentration. At 5 mg/mL (a 10 mg vial in 2 mL), 1.75 mg is 0.3500 mL, or 35 units on a U-100 syringe. 1.75 mg is the FDA-approved Vyleesi dose; change any input above to see your own numbers.
Is PT-141 FDA approved?
Yes, as bremelanotide (brand Vyleesi), approved in 2019 for hypoactive sexual desire disorder in premenopausal women. Other uses are off-label, and research-grade PT-141 is not the approved product. This tool is arithmetic only and not a recommendation.
How is PT-141 different from Viagra?
PT-141 is a melanocortin agonist that acts centrally in the brain's desire pathways, while sildenafil (Viagra) is a PDE5 inhibitor that works on blood flow. They act through entirely different mechanisms. This is background context, not advice.
What is the most common side effect of bremelanotide?
In the Phase III trials behind Vyleesi, nausea was the most common side effect, reported by roughly 40 percent of participants. This is factual background, not medical advice; discuss risks with a clinician.
How should reconstituted PT-141 be stored?
Follow the storage guidance for your specific product. Reconstituted peptide vials are generally refrigerated and used within a limited window. Regimio tracks a per-vial expiry countdown so you are not guessing.
Is this calculator exact?
Yes. It runs the arithmetic with no hidden rounding and shows the concentration to four decimal places, so your draw volume and units are precise.
Is this medical advice?
No. This calculator performs arithmetic on the values you enter. It does not recommend a dose, schedule, or source. Confirm anything you do with a qualified provider.
- 1Bremelanotide (PT-141) compound summary. PubChem, US National Library of Medicine
This tool performs reconstitution arithmetic only. It is not medical advice and does not recommend any compound, dose, schedule, or source. Always follow guidance from a qualified provider. See our medical disclaimer.